Julien Maupetit

Since I obtained my position, my principal activities have been: (i) structural bioinformatics and chemoinformatics web servers and programs development, (ii) structural bioinformatics assistance with biological wet laboratories, and (iii) platform and laboratory hosting, computing and storage resources administration.

The technics developped during my PhD applied to peptide structures appears strongly relevant. Hence, we designed PEP-FOLD, a fast method for large scale de novo peptide and miniprotein structure prediction.

In a post-genomic context, plenty of proteins, identified by their sequence, have no experimentaly resolved structure, and fall out the range of application of comparative modelling methods. The goal of my PhD was to explore a new de novo protein structure prediction approach.

Development and integration of a PDB files parser in a molecular visualization widget.

Transgenic mice genotyping.

Hepcidin involvement in particular hemochromatosis – IRE/IRP system in transgenic mice over-expressing the superoxyde dismutase.